[Effectiveness and safety of varenicline for smoking cessation]. / Effektivität und Sicherheit von Vareniclin zur Raucherentwöhnung.
Dtsch Med Wochenschr
; 137(18): 940-4, 2012 May.
Article
em De
| MEDLINE
| ID: mdl-22492478
ABSTRACT
Smoking is one of the major avoidable risks for mortality and morbidity. Thus developing new strategies for smoking cessation is a crucial medical challenge. Varenicline is an α4ß2 nicotinic acetylcholine receptor partial agonist developed especially for smoking cessation. Several trials proved the efficacy of varenicline and its superiority to other medications for smoking cessation (bupropion and nicotine replacement therapy). Varenicline was associated with severe cardiovascular and neuro-psychiatric side effects. This article discusses the current research data on efficacy and safety of varenicline therapy for smoking cessation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Quinoxalinas
/
Tabagismo
/
Benzazepinas
/
Abandono do Hábito de Fumar
/
Agonistas Nicotínicos
Limite:
Humans
Idioma:
De
Ano de publicação:
2012
Tipo de documento:
Article