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New Briarane diterpenoids from the gorgonian coral Junceella juncea.
Chang, Jiun-Yang; Liaw, Chia-Ching; Fazary, Ahmed Eid; Hwang, Tsong-Long; Shen, Ya-Ching.
Afiliação
  • Chang JY; School of Pharmacy, College of Medicine, National Taiwan University, Jen-Ai Rd. Sec. 1, Taipei 101-200, Taiwan.
  • Liaw CC; Institute of Marine Biotechnology and Resources, National Sun Yat-sen University, 70 Lien-Hai Road, Kaohsiung 80424, Taiwan.
  • Fazary AE; School of Pharmacy, College of Medicine, National Taiwan University, Jen-Ai Rd. Sec. 1, Taipei 101-200, Taiwan.
  • Hwang TL; School of Pharmacy, College of Medicine, National Taiwan University, Jen-Ai Rd. Sec. 1, Taipei 101-200, Taiwan.
  • Shen YC; Graduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan.
Mar Drugs ; 10(6): 1321-1330, 2012 Jun.
Article em En | MEDLINE | ID: mdl-22822375
ABSTRACT
Chemical investigation of Junceella juncea has resulted in the isolation of three new briaranes designated juncenolides M-O (1-3). The structures of these compounds were determined by spectroscopic analysis including 2D-NMR (COSY, HMBC and NOESY) and HRMS. Compound 1 is a new chlorinated briarane while compound 3 contains a rare methyl ester at C-16. The anti-inflammatory activities tested on superoxide anion generation and elastase release by human neutrophils in response to FMLP/CB were evaluated.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antozoários / Diterpenos / Anti-Inflamatórios Limite: Animals / Humans Idioma: En Ano de publicação: 2012 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antozoários / Diterpenos / Anti-Inflamatórios Limite: Animals / Humans Idioma: En Ano de publicação: 2012 Tipo de documento: Article