New Briarane diterpenoids from the gorgonian coral Junceella juncea.
Mar Drugs
; 10(6): 1321-1330, 2012 Jun.
Article
em En
| MEDLINE
| ID: mdl-22822375
ABSTRACT
Chemical investigation of Junceella juncea has resulted in the isolation of three new briaranes designated juncenolides M-O (1-3). The structures of these compounds were determined by spectroscopic analysis including 2D-NMR (COSY, HMBC and NOESY) and HRMS. Compound 1 is a new chlorinated briarane while compound 3 contains a rare methyl ester at C-16. The anti-inflammatory activities tested on superoxide anion generation and elastase release by human neutrophils in response to FMLP/CB were evaluated.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Antozoários
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Diterpenos
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Anti-Inflamatórios
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article