Factors influencing diagnosis of colorectal cancer: a hospital-based survey in China.
J Dig Dis
; 13(10): 517-24, 2012 Oct.
Article
em En
| MEDLINE
| ID: mdl-22988925
ABSTRACT
OBJECTIVE:
To investigate the diagnostic status of colorectal cancer (CRC) and the influence of early diagnosis and cancer stage in a tertiary care hospital in China.METHODS:
Face-to-face interviews were conducted in 364 consecutive CRC patients who had never participated in CRC screening. Initial symptoms, diagnosis and treatment delay were determined using a questionnaire. Factors influencing diagnostic status were analyzed using univariate analysis and logistic regression model.RESULTS:
A total of 307 patients were enrolled, in which 128 were with colon cancer and 179 with rectal cancer. The duration of diagnosis delay was significant longer than that of treatment delay. Unlike rectal cancer, colon cancer was likely to be treated at an advanced stage with a short interval between symptom onset and treatment. Colon cancer patients with a history of biliary tract or gallbladder stones, aged ≥ 50 years and with abdominal mass or intestinal obstruction as the initial symptom were diagnosed and treated much earlier. In rectal cancer, women and non-smokers were diagnosed and treated quickly. Factors correlated with early cancer stage were found in colon cancer, including bloody stool as the initial symptom (OR = 2.63, 95% CI 1.08-6.25, P = 0.034) and a history of appendectomy (OR = 4.00, 95% CI 1.15-14.29, P = 0.029).CONCLUSIONS:
The factors contributing to early cancer detection were identified but their clinical value is limited. Diagnosis by symptoms suggesting CRC needs to be improved and CRC screening should be vigorously promoted.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Retais
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Neoplasias do Colo
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Detecção Precoce de Câncer
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Hemorragia Gastrointestinal
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Obstrução Intestinal
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
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Qualitative_research
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Risk_factors_studies
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Screening_studies
Limite:
Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article