Association between left-handedness and allergy: a reappraisal.

There are conflicting reports in the literature about the possible association between left-handedness and immune disorders, including autoimmune diseases as well as allergies. In this study we compared the distribution of right- and left-handers, assessed with the Edinburgh Handedness Inventory, in a group of patients consulting an allergy clinic and a control population with a similar sex and age distribution. There was no overall association between left-handedness and allergies, although we found a tendency towards left-handedness in patients whose allergic symptoms started before puberty, suggesting that left-handers may have an increased predisposition to allergic disease that manifests itself during early life.