Your browser doesn't support javascript.
loading
[Long-term remission of Langerhans cell sarcoma by AIM regimen combined with involved-field irradiation].
Rinsho Ketsueki ; 53(11): 1911-5, 2012 Nov.
Article em Ja | MEDLINE | ID: mdl-23257672
A 67-year-old woman presented with a right inguinal mass in May 2006. CT scan showed lymph node involvement from the right inguinal to the common iliac and (18)F-FDG-PET revealed uptake in those areas. Biopsy results indicated Langerhans cell sarcoma (LCS). Interestingly, tumor cells expressed a high MIB1 index of 30%. We administered doxorubicin, ifosfamide, and mesna (AIM) chemotherapy, which were reported to effectively treat soft tissue sarcoma. After 5 courses of AIM therapy and involved-field radiation for residual diseases and a relapsed lesion on her right cervical node, she has remained in complete remission for more than 4 years. LCS is an intractable malignant disease and the optimal therapeutic strategy remains unclear. The AIM regimen combined with radiation therapy may be an effective treatment option for this disease.
Assuntos
Buscar no Google
Base de dados: MEDLINE Assunto principal: Radioquímica / Protocolos de Quimioterapia Combinada Antineoplásica / Sarcoma de Células de Langerhans Tipo de estudo: Diagnostic_studies Limite: Aged / Female / Humans Idioma: Ja Ano de publicação: 2012 Tipo de documento: Article
Buscar no Google
Base de dados: MEDLINE Assunto principal: Radioquímica / Protocolos de Quimioterapia Combinada Antineoplásica / Sarcoma de Células de Langerhans Tipo de estudo: Diagnostic_studies Limite: Aged / Female / Humans Idioma: Ja Ano de publicação: 2012 Tipo de documento: Article