[Antiproliferative activity of diclofenac at tumor cell cultures].
Eksp Klin Gastroenterol
; (5): 66-9, 2012.
Article
em Ru
| MEDLINE
| ID: mdl-23402174
ABSTRACT
It is known that for risk group's importance of early diagnostics and prevention of a cancer of a thick section of the intestines. The view was expressed that the use of nonsteroidal anti-inflammatory drugs prospectively. The article presents the data obtained after the determination of the effect on the domestic drug diclofenac on the ability of the lines of tumor cells of the human colon multiply this antiproliferativoe action on the dose of the drug. Used photometric method for determination antiproliferativoe action. In vitro determined the effect of the national drug diclofenac on the ability of the lines of tumor cells of the human colon multiply, and is set in a dose-dependent effect. It is established that under the action of NSAIDS metabolic activity of cells can both strengthen and weaken that depends on the line of tumor cells and the concentration of the drug.
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Base de dados:
MEDLINE
Assunto principal:
Anti-Inflamatórios não Esteroides
/
Diclofenaco
/
Neoplasias do Colo
/
Proliferação de Células
Limite:
Humans
Idioma:
Ru
Ano de publicação:
2012
Tipo de documento:
Article