Human papillomavirus types 16, 18, and 31 share similar endocytic requirements for entry.
J Virol
; 87(13): 7765-73, 2013 Jul.
Article
em En
| MEDLINE
| ID: mdl-23616662
ABSTRACT
Human papillomavirus type 18 (HPV18), one of the HPVs with malignant potential, enters cells by an unknown endocytic mechanism. The key cellular requirements for HPV18 endocytosis were tested in comparison to those for HPV16 and -31 endocytoses. HPV18 (like HPV16 and -31) entry was independent of clathrin, caveolin, dynamin, and lipid rafts but required actin polymerization and tetraspanin CD151, and the viruses were routed to the same LAMP-1-positive compartment. Hence, the viruses shared similar cellular requirements for endocytic entry.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Endocitose
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Papillomavirus Humano 16
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Papillomavirus Humano 18
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Internalização do Vírus
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Papillomavirus Humano 31
Limite:
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article