Mitochondrial dysfunction represses HIF-1α protein synthesis through AMPK activation in human hepatoma HepG2 cells.
Biochim Biophys Acta
; 1830(10): 4743-51, 2013 Oct.
Article
em En
| MEDLINE
| ID: mdl-23791554
Palavras-chave
AMP-activated protein kinase; AMPK; Adenosine monophosphate-activated protein kinase; CAIX; CCCP; DMEM; Dulbecco's modified Eagle medium; HCC; HIF-1α; Hypoxia-inducible factor-1α; LDHA; Mitochondrial dysfunction; Protein synthesis; ROS; RT-PCR; carbonic anhydrase IX; carbonyl cyanide m-chlorophenyl hydrazine; hepatocellular carcinoma; hypoxia-inducible factor-1α; lactate dehydrogenase A; mitochondrial DNA; mtDNA; reactive oxygen species; reverse transcription-polymerase chain reaction
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Adenilato Quinase
/
Carcinoma Hepatocelular
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Subunidade alfa do Fator 1 Induzível por Hipóxia
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Neoplasias Hepáticas
/
Mitocôndrias
Limite:
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article