Synthesis and evaluation of alpha-[[(2-haloethyl)amino]methyl]-2- nitro-1H-imidazole-1-ethanols as prodrugs of alpha-[(1-aziridinyl)methyl]-2- nitro-1H-imidazole-1-ethanol (RSU-1069) and its analogues which are radiosensitizers and bioreductively activated cytotoxins.
J Med Chem
; 33(9): 2603-10, 1990 Sep.
Article
em En
| MEDLINE
| ID: mdl-2391699
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Base de dados:
MEDLINE
Assunto principal:
Radiossensibilizantes
/
Pró-Fármacos
/
Citotoxinas
/
Misonidazol
/
Antineoplásicos
Limite:
Animals
Idioma:
En
Ano de publicação:
1990
Tipo de documento:
Article