The association between perceived emotional support, maternal mood, salivary cortisol, salivary cortisone, and the ratio between the two compounds in response to acute stress in second trimester pregnant women.
J Psychosom Res
; 75(4): 314-20, 2013 Oct.
Article
em En
| MEDLINE
| ID: mdl-24119936
ABSTRACT
OBJECTIVE:
Little is known about the effect of social support on the reactivity of the hypothalamic-pituitary-adrenal (HPA) axis during pregnancy. Moreover, when investigating the HPA axis most studies do not consider the activity of 11ß-hydroxysteroid dehydrogenase type 2 (11ß-HSD2), an enzyme within the salivary glands that inactivates cortisol to cortisone. This study explores the association between perceived emotional support and the maternal psychobiological stress response to a standardized naturalistic stressor by assessing maternal mood and the reactivity of salivary cortisol (SalF), salivary cortisone (SalE), and the SalE/(E+F) ratio as a marker of 11ß-HSD2 activity.METHODS:
Repeated saliva samples and measures of maternal mood were obtained from 34 healthy second trimester pregnant women undergoing amniocentesis which served as a psychological stressor. The pregnant women additionally responded to a questionnaire of perceived emotional support and provided sociodemographic (e.g., maternal educational degree) and pregnancy-specific data (e.g., planned versus unplanned pregnancy).RESULTS:
Perceived emotional support neither showed a significant effect on mood nor on the SalF or SalE response to stress. However, a moderately strong positive association was found between perceived emotional support and SalE/(E+F) (r=.49). Additionally, the final regression analysis revealed a significant negative relationship between educational degree, planned/unplanned pregnancy and SalE/(E+F).CONCLUSION:
Findings suggest a higher metabolization of cortisol to cortisone in pregnant women with higher emotional support. In contrast, higher maternal education and unplanned pregnancy appear to be associated with decreased salivary 11ß-HSD2 activity. The current study emphasizes the importance of taking the activity of 11ß-HSD2 into account when examining SalF.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Percepção Social
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Apoio Social
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Estresse Psicológico
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Cortisona
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Hidrocortisona
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Afeto
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Gestantes
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11-beta-Hidroxiesteroide Desidrogenase Tipo 2
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Emoções
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Amniocentese
Tipo de estudo:
Qualitative_research
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Risk_factors_studies
Limite:
Adult
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Female
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Humans
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Pregnancy
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article