High throughput molecular profiling reveals differential mutation patterns in intrahepatic cholangiocarcinomas arising in chronic advanced liver diseases.

Jang, Sejin; Chun, Sung-Min; Hong, Seoung-Mo; Sung, Chang Ohk; Park, Hosub; Kang, Hyo Jeong; Kim, Kyu-pyo; Lee, Young Joo; Yu, Eunsil

Jang, Sejin; Chun, Sung-Min; Hong, Seoung-Mo; Sung, Chang Ohk; Park, Hosub; Kang, Hyo Jeong; Kim, Kyu-pyo; Lee, Young Joo; Yu, Eunsil.

Afiliação

Jang S; 1] Department of Pathology, University of Ulsan College of Medicine, ASAN Medical Center, Seoul, Korea [2] ASAN Center for Cancer Genome Discovery, ASAN Institute for Life Sciences, University of Ulsan College of Medicine, ASAN Medical Center, Seoul, Korea.
Chun SM; 1] Department of Pathology, University of Ulsan College of Medicine, ASAN Medical Center, Seoul, Korea [2] ASAN Center for Cancer Genome Discovery, ASAN Institute for Life Sciences, University of Ulsan College of Medicine, ASAN Medical Center, Seoul, Korea.
Hong SM; Department of Pathology, University of Ulsan College of Medicine, ASAN Medical Center, Seoul, Korea.
Sung CO; Department of Pathology, University of Ulsan College of Medicine, ASAN Medical Center, Seoul, Korea.
Park H; Department of Pathology, University of Ulsan College of Medicine, ASAN Medical Center, Seoul, Korea.
Kang HJ; Department of Pathology, University of Ulsan College of Medicine, ASAN Medical Center, Seoul, Korea.
Kim KP; Department of Internal Medicine, University of Ulsan College of Medicine, ASAN Medical Center, Seoul, Korea.
Lee YJ; Department of Surgery, University of Ulsan College of Medicine, ASAN Medical Center, Seoul, Korea.
Yu E; 1] Department of Pathology, University of Ulsan College of Medicine, ASAN Medical Center, Seoul, Korea [2] ASAN Center for Cancer Genome Discovery, ASAN Institute for Life Sciences, University of Ulsan College of Medicine, ASAN Medical Center, Seoul, Korea.

Mod Pathol ; 27(5): 731-9, 2014 May.

Article em En | MEDLINE | ID: mdl-24186137

Assuntos

Neoplasias dos Ductos Biliares/genética; Colangiocarcinoma/genética; Hepatopatias/genética; Mutação; Proteínas Adaptadoras de Transdução de Sinal/genética; Adulto; Idoso; Neoplasias dos Ductos Biliares/patologia; Ductos Biliares Intra-Hepáticos/patologia; Colangiocarcinoma/patologia; Cromograninas; Análise Mutacional de DNA; Receptores ErbB/genética; Feminino; GTP Fosfo-Hidrolases/genética; Subunidades alfa Gs de Proteínas de Ligação ao GTP/genética; Humanos; Hepatopatias/patologia; Masculino; Espectrometria de Massas; Proteínas de Membrana/genética; Pessoa de Meia-Idade; Proteína 1 Homóloga a MutL; Proteínas Nucleares/genética; Proteínas Proto-Oncogênicas/genética; Proteínas Proto-Oncogênicas p21(ras); Proteínas ras/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias dos Ductos Biliares / Colangiocarcinoma / Hepatopatias / Mutação Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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