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Novel compounds lowering the cellular isoform of the human prion protein in cultured human cells.
Silber, B Michael; Gever, Joel R; Rao, Satish; Li, Zhe; Renslo, Adam R; Widjaja, Kartika; Wong, Casper; Giles, Kurt; Freyman, Yevgeniy; Elepano, Manuel; Irwin, John J; Jacobson, Matthew P; Prusiner, Stanley B.
Afiliação
  • Silber BM; Institute for Neurodegenerative Diseases, University of California, San Francisco, United States; Department of Neurology, University of California, San Francisco, United States; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, United States.
  • Gever JR; Institute for Neurodegenerative Diseases, University of California, San Francisco, United States; Department of Neurology, University of California, San Francisco, United States.
  • Rao S; Institute for Neurodegenerative Diseases, University of California, San Francisco, United States; Department of Neurology, University of California, San Francisco, United States.
  • Li Z; Institute for Neurodegenerative Diseases, University of California, San Francisco, United States; Department of Neurology, University of California, San Francisco, United States.
  • Renslo AR; Small Molecule Discovery Center, University of California, San Francisco, United States; Department of Pharmaceutical Chemistry, University of California, San Francisco, United States.
  • Widjaja K; Institute for Neurodegenerative Diseases, University of California, San Francisco, United States.
  • Wong C; Institute for Neurodegenerative Diseases, University of California, San Francisco, United States.
  • Giles K; Institute for Neurodegenerative Diseases, University of California, San Francisco, United States; Department of Neurology, University of California, San Francisco, United States.
  • Freyman Y; Institute for Neurodegenerative Diseases, University of California, San Francisco, United States.
  • Elepano M; Institute for Neurodegenerative Diseases, University of California, San Francisco, United States.
  • Irwin JJ; Department of Pharmaceutical Chemistry, University of California, San Francisco, United States.
  • Jacobson MP; Institute for Neurodegenerative Diseases, University of California, San Francisco, United States; Department of Pharmaceutical Chemistry, University of California, San Francisco, United States.
  • Prusiner SB; Institute for Neurodegenerative Diseases, University of California, San Francisco, United States; Department of Neurology, University of California, San Francisco, United States. Electronic address: stanley@ind.ucsf.edu.
Bioorg Med Chem ; 22(6): 1960-72, 2014 Mar 15.
Article em En | MEDLINE | ID: mdl-24530226
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Príons / Bibliotecas de Moléculas Pequenas Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Príons / Bibliotecas de Moléculas Pequenas Limite: Animals / Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article