Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemia.

Gattazzo, Cristina; Martini, Veronica; Frezzato, Federica; Trimarco, Valentina; Tibaldi, Elena; Castelli, Monica; Facco, Monica; Zonta, Francesca; Brunati, Anna Maria; Zambello, Renato; Semenzato, Gianpietro; Trentin, Livio

Gattazzo, Cristina; Martini, Veronica; Frezzato, Federica; Trimarco, Valentina; Tibaldi, Elena; Castelli, Monica; Facco, Monica; Zonta, Francesca; Brunati, Anna Maria; Zambello, Renato; Semenzato, Gianpietro; Trentin, Livio.

Afiliação

Gattazzo C; Departement of Medicine, Hematology and Clinical Immunology Branch, Padova University School of Medicine, Italy Venetian Institute of Molecular Medicine, Padova, Italy.
Martini V; Departement of Medicine, Hematology and Clinical Immunology Branch, Padova University School of Medicine, Italy Venetian Institute of Molecular Medicine, Padova, Italy.
Frezzato F; Departement of Medicine, Hematology and Clinical Immunology Branch, Padova University School of Medicine, Italy Venetian Institute of Molecular Medicine, Padova, Italy.
Trimarco V; Venetian Institute of Molecular Medicine, Padova, Italy.
Tibaldi E; Department of Molecular Medicine, University of Padova, Italy.
Castelli M; Departement of Medicine, Hematology and Clinical Immunology Branch, Padova University School of Medicine, Italy.
Facco M; Departement of Medicine, Hematology and Clinical Immunology Branch, Padova University School of Medicine, Italy Venetian Institute of Molecular Medicine, Padova, Italy.
Zonta F; Department of Molecular Medicine, University of Padova, Italy.
Brunati AM; Department of Molecular Medicine, University of Padova, Italy.
Zambello R; Departement of Medicine, Hematology and Clinical Immunology Branch, Padova University School of Medicine, Italy Venetian Institute of Molecular Medicine, Padova, Italy.
Semenzato G; Departement of Medicine, Hematology and Clinical Immunology Branch, Padova University School of Medicine, Italy Venetian Institute of Molecular Medicine, Padova, Italy.
Trentin L; Departement of Medicine, Hematology and Clinical Immunology Branch, Padova University School of Medicine, Italy Venetian Institute of Molecular Medicine, Padova, Italy livio.trentin@unipd.it.

Haematologica ; 99(6): 1069-77, 2014 Jun.

Article em En | MEDLINE | ID: mdl-24532043

Assuntos

Processamento Alternativo; Cortactina/genética; Leucemia Linfocítica Crônica de Células B/genética; Leucemia Linfocítica Crônica de Células B/metabolismo; Transdução de Sinais; Quinases da Família src/metabolismo; Adulto; Idoso; Idoso de 80 Anos ou mais; Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico; Linfócitos B/metabolismo; Linfócitos B/patologia; Estudos de Casos e Controles; Cortactina/metabolismo; Resistencia a Medicamentos Antineoplásicos/genética; Feminino; Expressão Gênica; Humanos; Leucemia Linfocítica Crônica de Células B/tratamento farmacológico; Masculino; Pessoa de Meia-Idade; Isoformas de Proteínas; Processamento de Proteína Pós-Traducional

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Transdução de Sinais / Processamento Alternativo / Quinases da Família src / Cortactina Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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