Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS.

Gbadegesin, Rasheed A; Hall, Gentzon; Adeyemo, Adebowale; Hanke, Nils; Tossidou, Irini; Burchette, James; Wu, Guanghong; Homstad, Alison; Sparks, Matthew A; Gomez, Jose; Jiang, Ruiji; Alonso, Andrea; Lavin, Peter; Conlon, Peter; Korstanje, Ron; Stander, M Christine; Shamsan, Ghaidan; Barua, Moumita; Spurney, Robert; Singhal, Pravin C; Kopp, Jeffrey B; Haller, Hermann; Howell, David; Pollak, Martin R; Shaw, Andrey S; Schiffer, Mario; Winn, Michelle P

Gbadegesin, Rasheed A; Hall, Gentzon; Adeyemo, Adebowale; Hanke, Nils; Tossidou, Irini; Burchette, James; Wu, Guanghong; Homstad, Alison; Sparks, Matthew A; Gomez, Jose; Jiang, Ruiji; Alonso, Andrea; Lavin, Peter; Conlon, Peter; Korstanje, Ron; Stander, M Christine; Shamsan, Ghaidan; Barua, Moumita; Spurney, Robert; Singhal, Pravin C; Kopp, Jeffrey B; Haller, Hermann; Howell, David; Pollak, Martin R; Shaw, Andrey S; Schiffer, Mario; Winn, Michelle P.

Afiliação

Gbadegesin RA; Departments of Pediatrics, Center for Human Genetics, Duke University Medical Center, Durham, North Carolina; rasheed.gbadegesin@duke.edu.
Hall G; Center for Human Genetics, Duke University Medical Center, Durham, North Carolina; Medicine, and.
Adeyemo A; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland;
Hanke N; Department of Nephrology, Hannover Medical School, Hannover, Germany; Mount Desert Island Biological Laboratory, Salisbury Cove, Maine;
Tossidou I; Department of Nephrology, Hannover Medical School, Hannover, Germany;
Burchette J; Pathology, and.
Wu G; Center for Human Genetics, Duke University Medical Center, Durham, North Carolina; Medicine, and.
Homstad A; Departments of Pediatrics, Center for Human Genetics, Duke University Medical Center, Durham, North Carolina;
Sparks MA; Medicine, and.
Gomez J; Medicine, and.
Jiang R; Departments of Pediatrics, Center for Human Genetics, Duke University Medical Center, Durham, North Carolina;
Alonso A; Departments of Pediatrics, Center for Human Genetics, Duke University Medical Center, Durham, North Carolina;
Lavin P; Center for Human Genetics, Duke University Medical Center, Durham, North Carolina; Medicine, and Trinity Health Kidney Centre, Tallaght Hospital, Trinity College, Dublin, Ireland;
Conlon P; Department of Nephrology, Beaumont Hospital, Dublin, Ireland;
Korstanje R; Mount Desert Island Biological Laboratory, Salisbury Cove, Maine; The Jackson Laboratory, Bar Harbor, Maine;
Stander MC; Howard Hughes Medical Institute, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri;
Shamsan G; Howard Hughes Medical Institute, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri;
Barua M; Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts;
Spurney R; Medicine, and.
Singhal PC; Feinstein Institute for Medical Research, North Shore-LIJ Health System, Manhasset, New York; and.
Kopp JB; Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Haller H; Department of Nephrology, Hannover Medical School, Hannover, Germany; Mount Desert Island Biological Laboratory, Salisbury Cove, Maine;
Howell D; Pathology, and.
Pollak MR; Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts;
Shaw AS; Howard Hughes Medical Institute, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri;
Schiffer M; Department of Nephrology, Hannover Medical School, Hannover, Germany; Mount Desert Island Biological Laboratory, Salisbury Cove, Maine;
Winn MP; Center for Human Genetics, Duke University Medical Center, Durham, North Carolina; Medicine, and.

J Am Soc Nephrol ; 25(9): 1991-2002, 2014 Sep.

Article em En | MEDLINE | ID: mdl-24676636

Assuntos

Glomerulosclerose Segmentar e Focal/genética; Proteínas dos Microfilamentos/genética; Mutação; Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Adulto; Idoso; Sequência de Aminoácidos; Animais; Movimento Celular/genética; Sequência Conservada; Proteínas Contráteis/genética; Proteínas do Citoesqueleto/metabolismo; Análise Mutacional de DNA; Modelos Animais de Doenças; Exoma; Feminino; Técnicas de Silenciamento de Genes; Barreira de Filtração Glomerular/metabolismo; Glomerulosclerose Segmentar e Focal/patologia; Humanos; Masculino; Camundongos; Pessoa de Meia-Idade; Dados de Sequência Molecular; Proteínas Mutantes/genética; Linhagem; Podócitos/metabolismo; Homologia de Sequência de Aminoácidos; Regulação para Cima; Peixe-Zebra; Proteínas de Peixe-Zebra/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glomerulosclerose Segmentar e Focal / Proteínas dos Microfilamentos / Mutação Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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