Lactobacillus rhamnosus HN001 decreases the severity of necrotizing enterocolitis in neonatal mice and preterm piglets: evidence in mice for a role of TLR9.

Good, Misty; Sodhi, Chhinder P; Ozolek, John A; Buck, Rachael H; Goehring, Karen C; Thomas, Debra L; Vikram, Amit; Bibby, Kyle; Morowitz, Michael J; Firek, Brian; Lu, Peng; Hackam, David J

Good, Misty; Sodhi, Chhinder P; Ozolek, John A; Buck, Rachael H; Goehring, Karen C; Thomas, Debra L; Vikram, Amit; Bibby, Kyle; Morowitz, Michael J; Firek, Brian; Lu, Peng; Hackam, David J.

Afiliação

Good M; Divisions of Newborn Medicine, Pediatrics, and.
Sodhi CP; Pediatric Surgery, and Departments of Surgery.
Ozolek JA; Pediatric Pathology, Children's Hospital of Pittsburgh; Pathology, the University of Pittsburgh School of Medicine;
Buck RH; Abbott Nutrition, a Division of Abbott Laboratories, Columbus, Ohio.
Goehring KC; Abbott Nutrition, a Division of Abbott Laboratories, Columbus, Ohio.
Thomas DL; Abbott Nutrition, a Division of Abbott Laboratories, Columbus, Ohio.
Vikram A; Departments of Civil and Environmental Engineering and.
Bibby K; Departments of Civil and Environmental Engineering and Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania;
Morowitz MJ; Pediatric Surgery, and Departments of Surgery.
Firek B; Pediatric Surgery, and Departments of Surgery.
Lu P; Pediatric Surgery, and Departments of Surgery.
Hackam DJ; Pediatric Surgery, and Departments of Surgery, david.hackam@chp.edu.

Am J Physiol Gastrointest Liver Physiol ; 306(11): G1021-32, 2014 Jun 01.

Article em En | MEDLINE | ID: mdl-24742987

Assuntos

Enterocolite Necrosante/prevenção & controle; Lacticaseibacillus rhamnosus/fisiologia; Probióticos/farmacologia; Receptor Toll-Like 9/metabolismo; Animais; Animais Recém-Nascidos; DNA Bacteriano/farmacologia; Enterocolite Necrosante/metabolismo; Enterocolite Necrosante/patologia; Camundongos; Nascimento Prematuro; Suínos; Receptor Toll-Like 9/genética

Palavras-chave

NF-κB; Toll-like receptor 4; Toll-like receptor 9; enterocyte; intestinal inflammation; necrotizing enterocolitis; prematurity; probiotics; sepsis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Probióticos / Enterocolite Necrosante / Lacticaseibacillus rhamnosus / Receptor Toll-Like 9 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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