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Pharmacokinetics-pharmacodynamics of the helicase-primase inhibitor pritelivir following treatment of wild-type or pritelivir-resistant virus infection in a murine herpes simplex virus 1 infection model.
Biswas, Subhajit; Sukla, Soumi; Goldner, Thomas; Field, Hugh J; Kropeit, Dirk; Paulsen, Daniela; Welbers, André; Ruebsamen-Schaeff, Helga; Zimmermann, Holger; Birkmann, Alexander.
Afiliação
  • Biswas S; Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.
  • Sukla S; Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.
  • Goldner T; AiCuris GmbH and Co. KG, Wuppertal, Germany.
  • Field HJ; Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.
  • Kropeit D; AiCuris GmbH and Co. KG, Wuppertal, Germany.
  • Paulsen D; AiCuris GmbH and Co. KG, Wuppertal, Germany.
  • Welbers A; AiCuris GmbH and Co. KG, Wuppertal, Germany.
  • Ruebsamen-Schaeff H; AiCuris GmbH and Co. KG, Wuppertal, Germany.
  • Zimmermann H; AiCuris GmbH and Co. KG, Wuppertal, Germany.
  • Birkmann A; AiCuris GmbH and Co. KG, Wuppertal, Germany alexander.birkmann@aicuris.com.
Antimicrob Agents Chemother ; 58(7): 3843-52, 2014 Jul.
Article em En | MEDLINE | ID: mdl-24752278

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Piridinas / Tiazóis / Herpesvirus Humano 1 / DNA Primase / DnaB Helicases / Herpes Simples Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Piridinas / Tiazóis / Herpesvirus Humano 1 / DNA Primase / DnaB Helicases / Herpes Simples Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article