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FFA-induced hepatic insulin resistance in vivo is mediated by PKCδ, NADPH oxidase, and oxidative stress.
Pereira, Sandra; Park, Edward; Mori, Yusaku; Haber, C Andrew; Han, Ping; Uchida, Toyoyoshi; Stavar, Laura; Oprescu, Andrei I; Koulajian, Khajag; Ivovic, Alexander; Yu, Zhiwen; Li, Deling; Bowman, Thomas A; Dewald, Jay; El-Benna, Jamel; Brindley, David N; Gutierrez-Juarez, Roger; Lam, Tony K T; Najjar, Sonia M; McKay, Robert A; Bhanot, Sanjay; Fantus, I George; Giacca, Adria.
Afiliação
  • Pereira S; Department of Physiology, University of Toronto, Toronto, Ontario, Canada;
  • Park E; Department of Physiology, University of Toronto, Toronto, Ontario, Canada;
  • Mori Y; Department of Physiology, University of Toronto, Toronto, Ontario, Canada;
  • Haber CA; Department of Physiology, University of Toronto, Toronto, Ontario, Canada;
  • Han P; Department of Physiology, University of Toronto, Toronto, Ontario, Canada;
  • Uchida T; Department of Physiology, University of Toronto, Toronto, Ontario, Canada;
  • Stavar L; Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; and.
  • Oprescu AI; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada;
  • Koulajian K; Department of Physiology, University of Toronto, Toronto, Ontario, Canada;
  • Ivovic A; Department of Physiology, University of Toronto, Toronto, Ontario, Canada;
  • Yu Z; Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; and.
  • Li D; Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; and.
  • Bowman TA; Center for Diabetes and Endocrine Research and the Department of Physiology and Pharmacology, University of Toledo College of Medicine, Toledo, Ohio; and.
  • Dewald J; Metabolic and Cardiovascular Diseases Laboratory, Alberta Institute for Human Nutrition, University of Alberta, Edmonton, Alberta, Canada;
  • El-Benna J; Inserm, U1149, CNRS-ERL8252, Centre de Recherche sur l'Inflammation, Paris, France; Laboratoire d'Excellence Inflamex, Faculté de Médecine, Université Paris Diderot, Sorbonne Paris Cité, Site Xavier Bichat, Paris, France;
  • Brindley DN; Metabolic and Cardiovascular Diseases Laboratory, Alberta Institute for Human Nutrition, University of Alberta, Edmonton, Alberta, Canada;
  • Gutierrez-Juarez R; Department of Medicine, Diabetes Research Center, Albert Einstein College of Medicine, Bronx, New York;
  • Lam TK; Department of Physiology, University of Toronto, Toronto, Ontario, Canada;
  • Najjar SM; Center for Diabetes and Endocrine Research and the Department of Physiology and Pharmacology, University of Toledo College of Medicine, Toledo, Ohio; and.
  • McKay RA; ISIS Pharmaceuticals Inc., Carlsbad, California.
  • Bhanot S; ISIS Pharmaceuticals Inc., Carlsbad, California.
  • Fantus IG; Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; and.
  • Giacca A; Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; and Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; adria.giacca@utoronto.ca.
Am J Physiol Endocrinol Metab ; 307(1): E34-46, 2014 Jul 01.
Article em En | MEDLINE | ID: mdl-24824652
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Quinase C / Resistência à Insulina / Estresse Oxidativo / NADPH Oxidases / Ácidos Graxos não Esterificados / Glucose / Fígado Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína Quinase C / Resistência à Insulina / Estresse Oxidativo / NADPH Oxidases / Ácidos Graxos não Esterificados / Glucose / Fígado Limite: Animals Idioma: En Ano de publicação: 2014 Tipo de documento: Article