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Transfusion-transmitted hepatitis E in Germany, 2013.
Huzly, D; Umhau, M; Bettinger, D; Cathomen, T; Emmerich, F; Hasselblatt, P; Hengel, H; Herzog, R; Kappert, O; Maassen, S; Schorb, E; Schulz-Huotari, C; Thimme, R; Unmüssig, R; Wenzel, J J; Panning, M.
Afiliação
  • Huzly D; Institute for Virology, University Medical Center, Freiburg, Germany.
Euro Surveill ; 19(21)2014 May 29.
Article em En | MEDLINE | ID: mdl-24906377
The reported IgG seroprevalence against hepatitis E virus (HEV) in German blood donations is 6.8%, and HEV RNA detected in 0.08%, but documented evidence for HEV transmission is lacking. We identified two donations from a single donor containing 120 IU HEV RNA/mL plasma and 490 IU/mL. An infectious dose of 7,056 IU HEV RNA was transmitted via apheresis platelets to an immunosuppressed patient who developed chronic HEV. Further, transmission was probable in an immunocompetent child.
Assuntos
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Base de dados: MEDLINE Assunto principal: RNA Viral / Vírus da Hepatite E / Hepatite E / Reação Transfusional Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Child / Humans País/Região como assunto: Europa Idioma: En Ano de publicação: 2014 Tipo de documento: Article
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Base de dados: MEDLINE Assunto principal: RNA Viral / Vírus da Hepatite E / Hepatite E / Reação Transfusional Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Child / Humans País/Região como assunto: Europa Idioma: En Ano de publicação: 2014 Tipo de documento: Article