Effect of siRNA against NF-&#954;B on sepsis­induced acute lung injury in a mouse model.

Jin, Li-Yan; Li, Cong-Feng; Zhu, Guang-Fa; Wu, Chun-Ting; Wang, Jun; Yan, Shu-Feng

Effect of siRNA against NF-κB on sepsisinduced acute lung injury in a mouse model.

Jin, Li-Yan; Li, Cong-Feng; Zhu, Guang-Fa; Wu, Chun-Ting; Wang, Jun; Yan, Shu-Feng.

Afiliação

Jin LY; Department of Infectious Disease, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, P.R. China.
Li CF; Department of Respiratory and Critical Care Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, P.R. China.
Zhu GF; Department of Respiratory and Critical Care Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, P.R. China.
Wu CT; Department of Respiratory and Critical Care Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, P.R. China.
Wang J; Department of Respiratory and Critical Care Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, P.R. China.
Yan SF; Department of Respiratory and Critical Care Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, P.R. China.

Mol Med Rep ; 10(2): 631-7, 2014 Aug.

Article em En | MEDLINE | ID: mdl-24913772

Assuntos

Lesão Pulmonar Aguda/patologia; Sepse/patologia; Fator de Transcrição RelA/metabolismo; Lesão Pulmonar Aguda/etiologia; Lesão Pulmonar Aguda/metabolismo; Animais; Ceco/lesões; Modelos Animais de Doenças; Células HEK293; Humanos; Interleucina-17/metabolismo; Interleucina-6/metabolismo; Masculino; Metaloproteinase 9 da Matriz/metabolismo; Camundongos; NF-kappa B/metabolismo; Interferência de RNA; RNA Mensageiro/metabolismo; RNA Interferente Pequeno/metabolismo; Sepse/etiologia; Sepse/metabolismo; Fator de Transcrição RelA/antagonistas & inibidores; Fator de Transcrição RelA/genética; Fator de Necrose Tumoral alfa/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sepse / Fator de Transcrição RelA / Lesão Pulmonar Aguda Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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