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Genome-wide association analysis identifies six new loci associated with forced vital capacity.
Loth, Daan W; Soler Artigas, María; Gharib, Sina A; Wain, Louise V; Franceschini, Nora; Koch, Beate; Pottinger, Tess D; Smith, Albert Vernon; Duan, Qing; Oldmeadow, Chris; Lee, Mi Kyeong; Strachan, David P; James, Alan L; Huffman, Jennifer E; Vitart, Veronique; Ramasamy, Adaikalavan; Wareham, Nicholas J; Kaprio, Jaakko; Wang, Xin-Qun; Trochet, Holly; Kähönen, Mika; Flexeder, Claudia; Albrecht, Eva; Lopez, Lorna M; de Jong, Kim; Thyagarajan, Bharat; Alves, Alexessander Couto; Enroth, Stefan; Omenaas, Ernst; Joshi, Peter K; Fall, Tove; Viñuela, Ana; Launer, Lenore J; Loehr, Laura R; Fornage, Myriam; Li, Guo; Wilk, Jemma B; Tang, Wenbo; Manichaikul, Ani; Lahousse, Lies; Harris, Tamara B; North, Kari E; Rudnicka, Alicja R; Hui, Jennie; Gu, Xiangjun; Lumley, Thomas; Wright, Alan F; Hastie, Nicholas D; Campbell, Susan; Kumar, Rajesh.
Afiliação
  • Loth DW; 1] Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands. [2] Netherlands Health Care Inspectorate, The Hague, the Netherlands. [3].
  • Soler Artigas M; 1] Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Leicester, UK. [2] National Institute for Health Research (NIHR) Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester, UK. [3].
  • Gharib SA; 1] Computational Medicine Core, Center for Lung Biology, University of Washington, Seattle, Washington, USA. [2] Department of Medicine, University of Washington, Seattle, Washington, USA. [3].
  • Wain LV; 1] Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Leicester, UK. [2] National Institute for Health Research (NIHR) Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester, UK. [3].
  • Franceschini N; 1] Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. [2] Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. [3].
  • Koch B; 1] Department of Internal Medicine B-Pneumology, Cardiology, Intensive Care and Infectious Diseases, University Hospital Greifswald, Greifswald, Germany. [2].
  • Pottinger TD; 1] Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA. [2].
  • Smith AV; 1] Iceland Heart Association, Kopavogur, Iceland. [2] University of Iceland, Reykjavik, Iceland. [3].
  • Duan Q; 1] Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA. [2].
  • Oldmeadow C; 1] Hunter Medical Research Institute, University of Newcastle, Newcastle, New South Wales, Australia. [2] Faculty of Health, University of Newcastle, Newcastle, New South Wales, Australia.
  • Lee MK; Institute of Health and Environment, Seoul National University, Seoul, South Korea.
  • Strachan DP; Division of Population Health Sciences and Education, St George's, University of London, London, UK.
  • James AL; 1] Department of Pulmonary Physiology and Sleep Medicine/West Australian Sleep Disorders Research Institute, Nedlands, Western Australia, Australia. [2] School of Medicine and Pharmacology, The University of Western Australia, Perth, Western Australia, Australia. [3] Busselton Population Medical Res
  • Huffman JE; Medical Research Council (MRC) Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, UK.
  • Vitart V; Medical Research Council (MRC) Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, UK.
  • Ramasamy A; 1] Respiratory Epidemiology and Public Health Group, National Heart and Lung Institute, Imperial College London, London, UK. [2] Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, Londo
  • Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.
  • Kaprio J; 1] Hjelt Institute, Department of Public Health, University of Helsinki, Helsinki, Finland. [2] National Institute for Health and Welfare (THL), Helsinki, Finland. [3] Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Wang XQ; Division of Biostatistics and Epidemiology, Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, USA.
  • Trochet H; Medical Research Council (MRC) Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, UK.
  • Kähönen M; Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland.
  • Flexeder C; Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
  • Albrecht E; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.
  • Lopez LM; 1] Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK. [2] Department of Psychology, University of Edinburgh, Edinburgh, UK.
  • de Jong K; 1] Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. [2] Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Thyagarajan B; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.
  • Alves AC; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Enroth S; 1] Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden. [2] Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
  • Omenaas E; 1] Centre for Clinical Research, Haukeland University Hospital, Bergen, Norway. [2] Department of Clinical Sciences, University of Bergen, Bergen, Norway.
  • Joshi PK; Centre for Population Health Sciences, Medical School, University of Edinburgh, Edinburgh, UK.
  • Fall T; 1] Science for Life Laboratory, Uppsala University, Uppsala, Sweden. [2] Molecular Epidemiology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
  • Viñuela A; Department of Twins Research and Genetic Epidemiology, King's College London, London, UK.
  • Launer LJ; Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA.
  • Loehr LR; 1] Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. [2] Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Fornage M; 1] Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, Texas, USA. [2] Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Li G; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA.
  • Wilk JB; Precision Medicine, Pfizer Global Research and Development, Cambridge, Massachusetts, USA.
  • Tang W; Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA.
  • Manichaikul A; 1] Division of Biostatistics and Epidemiology, Department of Public Health Sciences, University of Virginia, Charlottesville, Virginia, USA. [2] Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA.
  • Lahousse L; 1] Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands. [2] Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.
  • Harris TB; Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA.
  • North KE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
  • Rudnicka AR; Division of Population Health Sciences and Education, St George's, University of London, London, UK.
  • Hui J; PathWest Laboratory Medicine Washington, Nedlands, Western Australia, Australia.
  • Gu X; 1] Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, Texas, USA. [2] Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA.
  • Lumley T; Department of Statistics, University of Auckland, Auckland, New Zealand.
  • Wright AF; Medical Research Council (MRC) Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, UK.
  • Hastie ND; Medical Research Council (MRC) Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, UK.
  • Campbell S; Medical Research Council (MRC) Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh, Edinburgh, UK.
  • Kumar R; Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Nat Genet ; 46(7): 669-77, 2014 Jul.
Article em En | MEDLINE | ID: mdl-24929828

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma Humano / Capacidade Vital / Estudo de Associação Genômica Ampla / Loci Gênicos / Pneumopatias Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genoma Humano / Capacidade Vital / Estudo de Associação Genômica Ampla / Loci Gênicos / Pneumopatias Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article