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Nicotine causes genotoxic damage but is not metabolized during long-term exposure of human nasal miniorgan cultures.
Ginzkey, Christian; Steussloff, Gudrun; Koehler, Christian; Hackenberg, Stephan; Richter, Elmar; Hagen, Rudolf; Kleinsasser, Norbert H.
Afiliação
  • Ginzkey C; Department of Oto-Rhino-Laryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, Julius-Maximilian University Würzburg, Josef-Schneider-Str. 11, D-97080 Würzburg, Germany. Electronic address: ginzkey_c@ukw.de.
  • Steussloff G; Department of Oto-Rhino-Laryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, Julius-Maximilian University Würzburg, Josef-Schneider-Str. 11, D-97080 Würzburg, Germany.
  • Koehler C; Department of Oto-Rhino-Laryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, Julius-Maximilian University Würzburg, Josef-Schneider-Str. 11, D-97080 Würzburg, Germany.
  • Hackenberg S; Department of Oto-Rhino-Laryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, Julius-Maximilian University Würzburg, Josef-Schneider-Str. 11, D-97080 Würzburg, Germany.
  • Richter E; Walther Straub Institute, Department of Toxicology, Ludwig-Maximilians University Munich, Nussbaumstrasse 26, D-80336 Munich, Germany.
  • Hagen R; Department of Oto-Rhino-Laryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, Julius-Maximilian University Würzburg, Josef-Schneider-Str. 11, D-97080 Würzburg, Germany.
  • Kleinsasser NH; Department of Oto-Rhino-Laryngology, Plastic, Aesthetic and Reconstructive Head and Neck Surgery, Julius-Maximilian University Würzburg, Josef-Schneider-Str. 11, D-97080 Würzburg, Germany.
Toxicol Lett ; 229(1): 303-10, 2014 Aug 17.
Article em En | MEDLINE | ID: mdl-24983901

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Agonistas Nicotínicos / Mutagênicos / Mucosa Nasal / Nicotina Tipo de estudo: Etiology_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Agonistas Nicotínicos / Mutagênicos / Mucosa Nasal / Nicotina Tipo de estudo: Etiology_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2014 Tipo de documento: Article