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The KDM2B- let-7b -EZH2 axis in myelodysplastic syndromes as a target for combined epigenetic therapy.
Karoopongse, Ekapun; Yeung, Cecilia; Byon, John; Ramakrishnan, Aravind; Holman, Zaneta J; Jiang, Peter Y Z; Yu, Qiang; Deeg, H Joachim; Marcondes, A Mario.
Afiliação
  • Karoopongse E; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
  • Yeung C; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America; Department of Anatomic Pathology, University of Washington, Seattle, Washington, United States of America.
  • Byon J; Department of Hematology, University of Washington, Seattle, Washington, United States of America.
  • Ramakrishnan A; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
  • Holman ZJ; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America.
  • Jiang PY; Medical Oncology, Providence Regional Cancer Partnership and the Everett Clinic, Everett, Washington, United States of America.
  • Yu Q; Cancer Biology and Pharmacology, Genome Institute of Singapore, A*STAR (Agency for Science, Technology and Research), Biopolis, Singapore, China.
  • Deeg HJ; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
  • Marcondes AM; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America; Department of Medicine, University of Washington, Seattle, Washington, United States of America.
PLoS One ; 9(9): e107817, 2014.
Article em En | MEDLINE | ID: mdl-25225797
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / MicroRNAs / Proteínas F-Box / Epigênese Genética / Histona Desmetilases com o Domínio Jumonji / Complexo Repressor Polycomb 2 Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / MicroRNAs / Proteínas F-Box / Epigênese Genética / Histona Desmetilases com o Domínio Jumonji / Complexo Repressor Polycomb 2 Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article