Heterogeneity of mprF sequences in methicillin-resistant Staphylococcus aureus clinical isolates: role in cross-resistance between daptomycin and host defense antimicrobial peptides.

Bayer, Arnold S; Mishra, Nagendra N; Sakoulas, George; Nonejuie, Poochit; Nast, Cynthia C; Pogliano, Joseph; Chen, Kuan-Tsen; Ellison, Steven N; Yeaman, Michael R; Yang, Soo-Jin

Bayer, Arnold S; Mishra, Nagendra N; Sakoulas, George; Nonejuie, Poochit; Nast, Cynthia C; Pogliano, Joseph; Chen, Kuan-Tsen; Ellison, Steven N; Yeaman, Michael R; Yang, Soo-Jin.

Afiliação

Bayer AS; Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA The David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Mishra NN; Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA The David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Sakoulas G; University of California, San Diego School of Medicine, La Jolla, California, USA Department of Medicine, Sharp Memorial Hospital, San Diego, California, USA.
Nonejuie P; University of California, San Diego School of Medicine, La Jolla, California, USA.
Nast CC; The David Geffen School of Medicine at UCLA, Los Angeles, California, USA Cedars-Sinai Medical Center, Los Angeles, California, USA.
Pogliano J; University of California, San Diego School of Medicine, La Jolla, California, USA.
Chen KT; Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA.
Ellison SN; Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA.
Yeaman MR; Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA The David Geffen School of Medicine at UCLA, Los Angeles, California, USA Division of Molecular Medicine, Harbor-UCLA Medical Center, Torrance, California, USA.
Yang SJ; Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA The David Geffen School of Medicine at UCLA, Los Angeles, California, USA sjyang@ucla.edu.

Antimicrob Agents Chemother ; 58(12): 7462-7, 2014 Dec.

Article em En | MEDLINE | ID: mdl-25288091

Assuntos

Aminoaciltransferases/genética; Antibacterianos/farmacologia; Proteínas de Bactérias/genética; Regulação Bacteriana da Expressão Gênica; Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos; Staphylococcus aureus Resistente à Meticilina/genética; Polimorfismo de Nucleotídeo Único; Aminoaciltransferases/metabolismo; Peptídeos Catiônicos Antimicrobianos/farmacologia; Proteínas de Bactérias/metabolismo; Parede Celular/química; Parede Celular/efeitos dos fármacos; Parede Celular/metabolismo; Células Clonais; Daptomicina/farmacologia; Farmacorresistência Bacteriana Múltipla/genética; Humanos; Staphylococcus aureus Resistente à Meticilina/isolamento & purificação; Staphylococcus aureus Resistente à Meticilina/metabolismo; Testes de Sensibilidade Microbiana; Fosfolipídeos/química; Fosfolipídeos/metabolismo; Infecções Estafilocócicas/microbiologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Regulação Bacteriana da Expressão Gênica / Aminoaciltransferases / Polimorfismo de Nucleotídeo Único / Staphylococcus aureus Resistente à Meticilina / Antibacterianos Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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