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CATH: comprehensive structural and functional annotations for genome sequences.
Sillitoe, Ian; Lewis, Tony E; Cuff, Alison; Das, Sayoni; Ashford, Paul; Dawson, Natalie L; Furnham, Nicholas; Laskowski, Roman A; Lee, David; Lees, Jonathan G; Lehtinen, Sonja; Studer, Romain A; Thornton, Janet; Orengo, Christine A.
Afiliação
  • Sillitoe I; Institute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, WC1E 6BT, UK i.sillitoe@ucl.ac.uk.
  • Lewis TE; Institute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, WC1E 6BT, UK.
  • Cuff A; Institute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, WC1E 6BT, UK.
  • Das S; Institute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, WC1E 6BT, UK.
  • Ashford P; Institute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, WC1E 6BT, UK.
  • Dawson NL; Institute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, WC1E 6BT, UK.
  • Furnham N; London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
  • Laskowski RA; European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK.
  • Lee D; Institute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, WC1E 6BT, UK.
  • Lees JG; Institute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, WC1E 6BT, UK.
  • Lehtinen S; Institute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, WC1E 6BT, UK.
  • Studer RA; European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK.
  • Thornton J; European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK.
  • Orengo CA; Institute of Structural and Molecular Biology, UCL, 636 Darwin Building, Gower Street, WC1E 6BT, UK.
Nucleic Acids Res ; 43(Database issue): D376-81, 2015 Jan.
Article em En | MEDLINE | ID: mdl-25348408
ABSTRACT
The latest version of the CATH-Gene3D protein structure classification database (4.0, http//www.cathdb.info) provides annotations for over 235,000 protein domain structures and includes 25 million domain predictions. This article provides an update on the major developments in the 2 years since the last publication in this journal including significant improvements to the predictive power of our functional families (FunFams); the release of our 'current' putative domain assignments (CATH-B); a new, strictly non-redundant data set of CATH domains suitable for homology benchmarking experiments (CATH-40) and a number of improvements to the web pages.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estrutura Terciária de Proteína / Bases de Dados de Proteínas / Anotação de Sequência Molecular Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estrutura Terciária de Proteína / Bases de Dados de Proteínas / Anotação de Sequência Molecular Idioma: En Ano de publicação: 2015 Tipo de documento: Article