Adding fuel to the fire: immunogenic intensification.

O'Sullivan Coyne, Geraldine; Gulley, James L

O'Sullivan Coyne, Geraldine; Gulley, James L.

Afiliação

O'Sullivan Coyne G; a Genitourinary Malignancies Branch; Medical Oncology Service; National Cancer Institute; National Institutes of Health ; Bethesda , MD USA.

Hum Vaccin Immunother ; 10(11): 3306-12, 2014.

Article em En | MEDLINE | ID: mdl-25483630

Assuntos

Anticorpos Monoclonais/uso terapêutico; Antígenos de Neoplasias/imunologia; Vacinas Anticâncer/uso terapêutico; Imunoterapia/métodos; Neoplasias/imunologia; Anticorpos Monoclonais/imunologia; Vacinas Anticâncer/imunologia; Humanos; Neoplasias/terapia; Linfócitos T Citotóxicos/imunologia; Microambiente Tumoral/imunologia

Palavras-chave

APC, antigen-presenting cells; CARs, chimeric antigen receptors; HER2, epidermal growth factor receptor 2; MDSCs, myeloid-derived suppressor cells; MHC I, major histocompatibility class I molecules; PD-1, programmed death-1; PD-L1; PD-L1, programmed death-ligand-1; TAA, tumor-associated antigen; TAP, transporter of antigen processing; TILs, tumor infiltrating lymphocytes; Tregs, regulatory T cells; activated T cell; cancer; checkpoint inhibitor; immunogenic intensification; mAB, monoclonal antibodies; mCRPC, metastatic castration-resistant prostate cancer; vaccine

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas Anticâncer / Imunoterapia / Anticorpos Monoclonais / Antígenos de Neoplasias / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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