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The progressive adaptation of a georgian isolate of African swine fever virus to vero cells leads to a gradual attenuation of virulence in swine corresponding to major modifications of the viral genome.
Krug, Peter W; Holinka, Lauren G; O'Donnell, Vivian; Reese, Bo; Sanford, Brenton; Fernandez-Sainz, Ignacio; Gladue, Douglas P; Arzt, Jonathan; Rodriguez, Luis; Risatti, Guillermo R; Borca, Manuel V.
Afiliação
  • Krug PW; Agricultural Research Service, U.S. Department of Agriculture, Plum Island Animal Disease Center, Greenport, New York, USA.
  • Holinka LG; Agricultural Research Service, U.S. Department of Agriculture, Plum Island Animal Disease Center, Greenport, New York, USA.
  • O'Donnell V; Agricultural Research Service, U.S. Department of Agriculture, Plum Island Animal Disease Center, Greenport, New York, USA Department of Pathobiology and Veterinary Science, CANHR, University of Connecticut, Storrs, Connecticut, USA.
  • Reese B; Center for Applied Genetics and Technology, University of Connecticut, Storrs, Connecticut, USA.
  • Sanford B; Agricultural Research Service, U.S. Department of Agriculture, Plum Island Animal Disease Center, Greenport, New York, USA.
  • Fernandez-Sainz I; Agricultural Research Service, U.S. Department of Agriculture, Plum Island Animal Disease Center, Greenport, New York, USA Department of Pathobiology and Veterinary Science, CANHR, University of Connecticut, Storrs, Connecticut, USA.
  • Gladue DP; Agricultural Research Service, U.S. Department of Agriculture, Plum Island Animal Disease Center, Greenport, New York, USA Department of Pathobiology and Veterinary Science, CANHR, University of Connecticut, Storrs, Connecticut, USA.
  • Arzt J; Agricultural Research Service, U.S. Department of Agriculture, Plum Island Animal Disease Center, Greenport, New York, USA.
  • Rodriguez L; Agricultural Research Service, U.S. Department of Agriculture, Plum Island Animal Disease Center, Greenport, New York, USA.
  • Risatti GR; Department of Pathobiology and Veterinary Science, CANHR, University of Connecticut, Storrs, Connecticut, USA.
  • Borca MV; Agricultural Research Service, U.S. Department of Agriculture, Plum Island Animal Disease Center, Greenport, New York, USA manuel.borca@ars.usda.gov.
J Virol ; 89(4): 2324-32, 2015 Feb.
Article em En | MEDLINE | ID: mdl-25505073
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adaptação Biológica / Inoculações Seriadas / Deleção de Sequência / Vírus da Febre Suína Africana / Mutação Limite: Animals País/Região como assunto: Europa Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adaptação Biológica / Inoculações Seriadas / Deleção de Sequência / Vírus da Febre Suína Africana / Mutação Limite: Animals País/Região como assunto: Europa Idioma: En Ano de publicação: 2015 Tipo de documento: Article