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A novel carboline derivative inhibits nitric oxide formation in macrophages independent of effects on tumor necrosis factor α and interleukin-1ß expression.
Grodzki, Ana Cristina G; Poola, Bhaskar; Pasupuleti, Nagarekha; Nantz, Michael H; Lein, Pamela J; Gorin, Fredric.
Afiliação
  • Grodzki AC; Department of Molecular Biosciences, School of Veterinary Medicine (A.C.G.G., F.G., P.J.L.), and Department of Neurology, School of Medicine (N.P., F.G.), University of California, Davis, California; and Department of Chemistry, University of Louisville, Louisville, Kentucky (B.P., M.H.N.) cgrodzki@
  • Poola B; Department of Molecular Biosciences, School of Veterinary Medicine (A.C.G.G., F.G., P.J.L.), and Department of Neurology, School of Medicine (N.P., F.G.), University of California, Davis, California; and Department of Chemistry, University of Louisville, Louisville, Kentucky (B.P., M.H.N.).
  • Pasupuleti N; Department of Molecular Biosciences, School of Veterinary Medicine (A.C.G.G., F.G., P.J.L.), and Department of Neurology, School of Medicine (N.P., F.G.), University of California, Davis, California; and Department of Chemistry, University of Louisville, Louisville, Kentucky (B.P., M.H.N.).
  • Nantz MH; Department of Molecular Biosciences, School of Veterinary Medicine (A.C.G.G., F.G., P.J.L.), and Department of Neurology, School of Medicine (N.P., F.G.), University of California, Davis, California; and Department of Chemistry, University of Louisville, Louisville, Kentucky (B.P., M.H.N.).
  • Lein PJ; Department of Molecular Biosciences, School of Veterinary Medicine (A.C.G.G., F.G., P.J.L.), and Department of Neurology, School of Medicine (N.P., F.G.), University of California, Davis, California; and Department of Chemistry, University of Louisville, Louisville, Kentucky (B.P., M.H.N.).
  • Gorin F; Department of Molecular Biosciences, School of Veterinary Medicine (A.C.G.G., F.G., P.J.L.), and Department of Neurology, School of Medicine (N.P., F.G.), University of California, Davis, California; and Department of Chemistry, University of Louisville, Louisville, Kentucky (B.P., M.H.N.).
J Pharmacol Exp Ther ; 352(3): 438-47, 2015 Mar.
Article em En | MEDLINE | ID: mdl-25538105
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carbolinas / Fator de Necrose Tumoral alfa / Interleucina-1beta / Macrófagos / Óxido Nítrico Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carbolinas / Fator de Necrose Tumoral alfa / Interleucina-1beta / Macrófagos / Óxido Nítrico Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article