Mathematical and computational modeling in biology at multiple scales.
Theor Biol Med Model
; 11: 52, 2014 Dec 27.
Article
em En
| MEDLINE
| ID: mdl-25542608
ABSTRACT
A variety of topics are reviewed in the area of mathematical and computational modeling in biology, covering the range of scales from populations of organisms to electrons in atoms. The use of maximum entropy as an inference tool in the fields of biology and drug discovery is discussed. Mathematical and computational methods and models in the areas of epidemiology, cell physiology and cancer are surveyed. The technique of molecular dynamics is covered, with special attention to force fields for protein simulations and methods for the calculation of solvation free energies. The utility of quantum mechanical methods in biophysical and biochemical modeling is explored. The field of computational enzymology is examined.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Simulação por Computador
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article