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Developing Adnectins that target SRC co-activator binding to PXR: a structural approach toward understanding promiscuity of PXR.
Khan, Javed A; Camac, Daniel M; Low, Simon; Tebben, Andrew J; Wensel, David L; Wright, Martin C; Su, Julie; Jenny, Victoria; Gupta, Ruchira Das; Ruzanov, Max; Russo, Katie A; Bell, Aneka; An, Yongmi; Bryson, James W; Gao, Mian; Gambhire, Pallavi; Baldwin, Eric T; Gardner, Daniel; Cavallaro, Cullen L; Duncia, John V; Hynes, John.
Afiliação
  • Khan JA; Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA. Electronic address: javed.khan@bms.com.
  • Camac DM; Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA.
  • Low S; Adnexus, 100 Beaver Street, Waltham, MA 02453, USA.
  • Tebben AJ; Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA.
  • Wensel DL; Adnexus, 100 Beaver Street, Waltham, MA 02453, USA.
  • Wright MC; Adnexus, 100 Beaver Street, Waltham, MA 02453, USA.
  • Su J; Adnexus, 100 Beaver Street, Waltham, MA 02453, USA.
  • Jenny V; Adnexus, 100 Beaver Street, Waltham, MA 02453, USA.
  • Gupta RD; Adnexus, 100 Beaver Street, Waltham, MA 02453, USA.
  • Ruzanov M; Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA.
  • Russo KA; Adnexus, 100 Beaver Street, Waltham, MA 02453, USA.
  • Bell A; Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA.
  • An Y; Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA.
  • Bryson JW; Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA.
  • Gao M; Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA.
  • Gambhire P; Adnexus, 100 Beaver Street, Waltham, MA 02453, USA.
  • Baldwin ET; Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA.
  • Gardner D; Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA.
  • Cavallaro CL; Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA.
  • Duncia JV; Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA.
  • Hynes J; Bristol-Myers Squibb Research and Development, PO Box 4000, Princeton, NJ 08543-4000, USA.
J Mol Biol ; 427(4): 924-942, 2015 Feb 27.
Article em En | MEDLINE | ID: mdl-25579995

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ureia / Valina / Receptores de Esteroides / Receptores CCR1 / Coativador 1 de Receptor Nuclear Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ureia / Valina / Receptores de Esteroides / Receptores CCR1 / Coativador 1 de Receptor Nuclear Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article