Cucurbiturils as supramolecular inhibitors of DNA restriction by type II endonucleases.
Org Biomol Chem
; 13(10): 2866-9, 2015 Mar 14.
Article
em En
| MEDLINE
| ID: mdl-25581012
ABSTRACT
Cucurbiturils (CB6 and CB7) were shown to inhibit the enzymatically catalyzed restriction of plasmids and linear DNA. This effect can be inverted by supramolecular masking of the macrocycles through competitive complexation with polyamines. These experiments provide supramolecular control of biocatalytic processes.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
DNA
/
Compostos Macrocíclicos
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Endonucleases
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Inibidores Enzimáticos
Limite:
Animals
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article