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Clinical trials. Rituximab for maintenance of remission in AAV.
Tanna, Anisha; Pusey, Charles.
Afiliação
  • Tanna A; Renal and Vascular Inflammation Section, Department of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.
  • Pusey C; Renal and Vascular Inflammation Section, Department of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK.
Nat Rev Nephrol ; 11(3): 131-2, 2015 Mar.
Article em En | MEDLINE | ID: mdl-25599619
ABSTRACT
Maintenance therapy for antineutrophil cytoplasmic antibody-associated vasculitis (AAV) should reduce rates of relapse with minimal toxicity. The MAINRITSAN trial­the first randomized controlled trial to compare the efficacies of rituximab and azathioprine in AAV remission maintenance­ has demonstrated a superior outcome using rituximab. These data have important implications for the management of AAV.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Azatioprina / Vasculite Associada a Anticorpo Anticitoplasma de Neutrófilos / Anticorpos Monoclonais Murinos / Imunossupressores Tipo de estudo: Clinical_trials Limite: Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Azatioprina / Vasculite Associada a Anticorpo Anticitoplasma de Neutrófilos / Anticorpos Monoclonais Murinos / Imunossupressores Tipo de estudo: Clinical_trials Limite: Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article