Dimeric drug polymeric nanoparticles with exceptionally high drug loading and quantitative loading efficiency.

Cai, Kaimin; He, Xi; Song, Ziyuan; Yin, Qian; Zhang, Yanfeng; Uckun, Fatih M; Jiang, Chen; Cheng, Jianjun

Cai, Kaimin; He, Xi; Song, Ziyuan; Yin, Qian; Zhang, Yanfeng; Uckun, Fatih M; Jiang, Chen; Cheng, Jianjun.

Afiliação

Cai K; Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
He X; Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Song Z; Key Laboratory of Smart Drug Delivery, Ministry of Education, Department of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai 201203, China.
Yin Q; Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Zhang Y; Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Uckun FM; Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Jiang C; §Division of Hematology-Oncology, Systems Immunobiology Laboratory, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, California 90027, United States.
Cheng J; â¥Department of Pediatrics and Norris Comprehensive Cancer Center, University of Southern California, Keck School of Medicine, Los Angeles, California 90027, United States.

J Am Chem Soc ; 137(10): 3458-61, 2015 Mar 18.

Article em En | MEDLINE | ID: mdl-25741752

Assuntos

Dimerização; Portadores de Fármacos/química; Liberação Controlada de Fármacos; Nanopartículas/química; Poliésteres/química; Polietilenoglicóis/química; Interações Hidrofóbicas e Hidrofílicas; Modelos Moleculares

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poliésteres / Polietilenoglicóis / Portadores de Fármacos / Dimerização / Nanopartículas / Liberação Controlada de Fármacos Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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