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Design, synthesis and biological evaluation of functionalized phthalimides: a new class of antimalarials and inhibitors of falcipain-2, a major hemoglobinase of malaria parasite.
Singh, Anil K; Rajendran, Vinoth; Pant, Akansha; Ghosh, Prahlad C; Singh, Neelu; Latha, N; Garg, Sandeep; Pandey, Kailash C; Singh, Brajendra K; Rathi, Brijesh.
Afiliação
  • Singh AK; Bio-organic Research Laboratory, Department of Chemistry, University of Delhi, Delhi 110 007, India.
  • Rajendran V; Department of Biochemistry, University of Delhi South Campus, New Delhi 110 021, India.
  • Pant A; National Institute of Malaria Research, Host-Parasite Interaction Biology Group, Lab. No. 219, Sector-8 Dwarka, New Delhi 110077, India.
  • Ghosh PC; Department of Biochemistry, University of Delhi South Campus, New Delhi 110 021, India.
  • Singh N; Bioinformatics Infrastructure Facility, Sri Venkateswara College, University of Delhi South Campus, New Delhi 110 021, India.
  • Latha N; Bioinformatics Infrastructure Facility, Sri Venkateswara College, University of Delhi South Campus, New Delhi 110 021, India.
  • Garg S; Department of Zoology, Smt. Chandibai Himathmal Mansukhani College (University of Mumbai), Ulhasnagar, Thane, Maharashtra 421 003, India.
  • Pandey KC; National Institute of Malaria Research, Host-Parasite Interaction Biology Group, Lab. No. 219, Sector-8 Dwarka, New Delhi 110077, India.
  • Singh BK; Bio-organic Research Laboratory, Department of Chemistry, University of Delhi, Delhi 110 007, India.
  • Rathi B; Bio-organic Research Laboratory, Department of Chemistry, University of Delhi, Delhi 110 007, India; Department of Chemistry, Hans Raj College, University of Delhi, Delhi 110 007, India. Electronic address: brathi@svc.ac.in.
Bioorg Med Chem ; 23(8): 1817-27, 2015 Apr 15.
Article em En | MEDLINE | ID: mdl-25766631
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ftalimidas / Plasmodium falciparum / Cisteína Endopeptidases / Antimaláricos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ftalimidas / Plasmodium falciparum / Cisteína Endopeptidases / Antimaláricos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article