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A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication.
Zhao, Yongqian; Soh, Tingjin Sherryl; Zheng, Jie; Chan, Kitti Wing Ki; Phoo, Wint Wint; Lee, Chin Chin; Tay, Moon Y F; Swaminathan, Kunchithapadam; Cornvik, Tobias C; Lim, Siew Pheng; Shi, Pei-Yong; Lescar, Julien; Vasudevan, Subhash G; Luo, Dahai.
Afiliação
  • Zhao Y; Program in Emerging Infectious Diseases, DUKE-NUS Graduate Medical School, Singapore; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore.
  • Soh TS; School of Biological Sciences, Nanyang Technological University, Singapore; Novartis Institute for Tropical Diseases, Singapore.
  • Zheng J; School of Biological Sciences, Nanyang Technological University, Singapore.
  • Chan KW; Program in Emerging Infectious Diseases, DUKE-NUS Graduate Medical School, Singapore.
  • Phoo WW; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
  • Lee CC; Program in Emerging Infectious Diseases, DUKE-NUS Graduate Medical School, Singapore.
  • Tay MY; Program in Emerging Infectious Diseases, DUKE-NUS Graduate Medical School, Singapore.
  • Swaminathan K; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore; Department of Biological Sciences, National University of Singapore, Singapore.
  • Cornvik TC; School of Biological Sciences, Nanyang Technological University, Singapore.
  • Lim SP; Novartis Institute for Tropical Diseases, Singapore.
  • Shi PY; Novartis Institute for Tropical Diseases, Singapore.
  • Lescar J; School of Biological Sciences, Nanyang Technological University, Singapore; UPMC UMRS CR7-CNRS ERL 8255-INSERM U1135 Centre d'Immunologie et des Maladies Infectieuses, Centre Hospitalier Universitaire Pitié-Salpêtrière, Faculté de Médecine Pierre et Marie Curie, Paris, France.
  • Vasudevan SG; Program in Emerging Infectious Diseases, DUKE-NUS Graduate Medical School, Singapore; NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore.
  • Luo D; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
PLoS Pathog ; 11(3): e1004682, 2015 Mar.
Article em En | MEDLINE | ID: mdl-25775415
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Replicação Viral / Proteínas não Estruturais Virais / Vírus da Dengue Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Replicação Viral / Proteínas não Estruturais Virais / Vírus da Dengue Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2015 Tipo de documento: Article