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Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis in Aedes aegypti.
Basu, Sanjay; Aryan, Azadeh; Overcash, Justin M; Samuel, Glady Hazitha; Anderson, Michelle A E; Dahlem, Timothy J; Myles, Kevin M; Adelman, Zach N.
Afiliação
  • Basu S; Fralin Life Science Institute and Department of Entomology, Virginia Tech, Blacksburg, VA 24061; and.
  • Aryan A; Fralin Life Science Institute and Department of Entomology, Virginia Tech, Blacksburg, VA 24061; and.
  • Overcash JM; Fralin Life Science Institute and Department of Entomology, Virginia Tech, Blacksburg, VA 24061; and.
  • Samuel GH; Fralin Life Science Institute and Department of Entomology, Virginia Tech, Blacksburg, VA 24061; and.
  • Anderson MA; Fralin Life Science Institute and Department of Entomology, Virginia Tech, Blacksburg, VA 24061; and.
  • Dahlem TJ; Mutation Generation and Detection Core, Health Science Center Core Research Facility, University of Utah, Salt Lake City, UT 84132.
  • Myles KM; Fralin Life Science Institute and Department of Entomology, Virginia Tech, Blacksburg, VA 24061; and mylesk@vt.edu zachadel@vt.edu.
  • Adelman ZN; Fralin Life Science Institute and Department of Entomology, Virginia Tech, Blacksburg, VA 24061; and mylesk@vt.edu zachadel@vt.edu.
Proc Natl Acad Sci U S A ; 112(13): 4038-43, 2015 Mar 31.
Article em En | MEDLINE | ID: mdl-25775608

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mutagênese Insercional / Aedes / Inativação Gênica / Reparo do DNA / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mutagênese Insercional / Aedes / Inativação Gênica / Reparo do DNA / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article