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Bioinformatic analysis of neurotropic HIV envelope sequences identifies polymorphisms in the gp120 bridging sheet that increase macrophage-tropism through enhanced interactions with CCR5.
Mefford, Megan E; Kunstman, Kevin; Wolinsky, Steven M; Gabuzda, Dana.
Afiliação
  • Mefford ME; Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address: megan_mefford@hms.harvard.edu.
  • Kunstman K; Northwestern University Medical School, Chicago, IL, USA. Electronic address: kunstman@northwestern.edu.
  • Wolinsky SM; Northwestern University Medical School, Chicago, IL, USA. Electronic address: s-wolinsky@northwestern.edu.
  • Gabuzda D; Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Neurology (Microbiology and Immunobiology), Harvard Medical School, Boston, MA, USA. Electronic address: dana_gabuzda@dfci.harvard.edu.
Virology ; 481: 210-22, 2015 Jul.
Article em En | MEDLINE | ID: mdl-25797607
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Proteína gp120 do Envelope de HIV / Infecções por HIV / HIV-1 / Receptores CCR5 / Tropismo Viral / Macrófagos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Proteína gp120 do Envelope de HIV / Infecções por HIV / HIV-1 / Receptores CCR5 / Tropismo Viral / Macrófagos Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article