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Age at Epstein-Barr virus infection and Epstein-Barr virus nuclear antigen-1 antibodies in Swedish children.
Simon, K Claire; Saghafian-Hedengren, Shanie; Sverremark-Ekström, Eva; Nilsson, Caroline; Ascherio, Alberto.
Afiliação
  • Simon KC; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA; Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: ksimon@hsph.harvard.edu.
  • Saghafian-Hedengren S; Department of Immunology, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.
  • Sverremark-Ekström E; Department of Immunology, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.
  • Nilsson C; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet and Sachs' Children's Hospital, Södersjukhuset, Stockholm, Sweden.
  • Ascherio A; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA; Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
Mult Scler Relat Disord ; 1(3): 136-8, 2012 Jul.
Article em En | MEDLINE | ID: mdl-25877079
ABSTRACT
There is strong evidence supporting a role for Epstein-Barr virus (EBV) in the etiopathogenesis of multiple sclerosis (MS). Because of the strong association between antibody (Ab) titer against EBV nuclear antigen 1 (EBNA1) and late age at EBV infection, manifested as infectious mononucleosis (IM), and MS risk, we sought to determine whether age at primary EBV infection was associated with subsequent anti-EBNA1 Ab titer in a longitudinal study of Swedish children with EBV seropositivity and anti-EBNA1 Ab titers measured at ages 2, 5, and 10.
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Observational_studies / Risk_factors_studies Idioma: En Ano de publicação: 2012 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Observational_studies / Risk_factors_studies Idioma: En Ano de publicação: 2012 Tipo de documento: Article