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Effect of genetic variations on ticagrelor plasma levels and clinical outcomes.
Varenhorst, Christoph; Eriksson, Niclas; Johansson, Åsa; Barratt, Bryan J; Hagström, Emil; Åkerblom, Axel; Syvänen, Ann-Christine; Becker, Richard C; James, Stefan K; Katus, Hugo A; Husted, Steen; Steg, Ph Gabriel; Siegbahn, Agneta; Voora, Deepak; Teng, Renli; Storey, Robert F; Wallentin, Lars.
Afiliação
  • Varenhorst C; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden Uppsala Clinical Research Center, Uppsala University, Dag Hammarskjölds väg 14B, level 1, SE-751 85 Uppsala, Sweden christoph.varenhorst@ucr.uu.se.
  • Eriksson N; Uppsala Clinical Research Center, Uppsala University, Dag Hammarskjölds väg 14B, level 1, SE-751 85 Uppsala, Sweden.
  • Johansson Å; Uppsala Clinical Research Center, Uppsala University, Dag Hammarskjölds väg 14B, level 1, SE-751 85 Uppsala, Sweden Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
  • Barratt BJ; AstraZeneca R&D, Alderley Park, Cheshire, UK.
  • Hagström E; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden Uppsala Clinical Research Center, Uppsala University, Dag Hammarskjölds väg 14B, level 1, SE-751 85 Uppsala, Sweden.
  • Åkerblom A; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden Uppsala Clinical Research Center, Uppsala University, Dag Hammarskjölds väg 14B, level 1, SE-751 85 Uppsala, Sweden.
  • Syvänen AC; Department of Medical Sciences, Molecular Medicine, Uppsala University, Uppsala, Sweden.
  • Becker RC; Division of Cardiovascular Health and Disease, Heart, Lung and Vascular Institute, Academic Health Center, Cincinnati, OH, USA Heart, Lung and Vascular Institute, Cardiovascular Services, University of Cincinnati Health System, Cincinnati, OH, USA.
  • James SK; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden Uppsala Clinical Research Center, Uppsala University, Dag Hammarskjölds väg 14B, level 1, SE-751 85 Uppsala, Sweden.
  • Katus HA; Medizinische Klinik, Universitätsklinikum Heidelberg, Heidelberg, Germany.
  • Husted S; Medical Department, Hospital Unit West, Herning/Holstebro, Denmark.
  • Steg PG; INSERM-Unité 1148, Paris, France Assistance Publique-Hôpitaux de Paris, Département Hospitalo-Universitaire FIRE, Hôpital Bichat, Paris, France Université Paris-Diderot, Sorbonne-Paris Cité, Paris, France NHLI Imperial College, ICMS, Royal Brompton Hospital, London, UK.
  • Siegbahn A; Uppsala Clinical Research Center, Uppsala University, Dag Hammarskjölds väg 14B, level 1, SE-751 85 Uppsala, Sweden Department of Medical Sciences, Clinical Chemistry, Uppsala University, Uppsala, Sweden.
  • Voora D; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA.
  • Teng R; AstraZeneca LP, Wilmington, DE, USA.
  • Storey RF; Department of Cardiovascular Science, University of Sheffield, Sheffield, UK.
  • Wallentin L; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden Uppsala Clinical Research Center, Uppsala University, Dag Hammarskjölds väg 14B, level 1, SE-751 85 Uppsala, Sweden.
Eur Heart J ; 36(29): 1901-12, 2015 Aug 01.
Article em En | MEDLINE | ID: mdl-25935875
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adenosina / Glucuronosiltransferase / Transportadores de Ânions Orgânicos / Citocromo P-450 CYP3A / Síndrome Coronariana Aguda / Antagonistas do Receptor Purinérgico P2Y Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adenosina / Glucuronosiltransferase / Transportadores de Ânions Orgânicos / Citocromo P-450 CYP3A / Síndrome Coronariana Aguda / Antagonistas do Receptor Purinérgico P2Y Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2015 Tipo de documento: Article