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Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors.
Lemos, Dario R; Babaeijandaghi, Farshad; Low, Marcela; Chang, Chih-Kai; Lee, Sunny T; Fiore, Daniela; Zhang, Regan-Heng; Natarajan, Anuradha; Nedospasov, Sergei A; Rossi, Fabio M V.
Afiliação
  • Lemos DR; 1] Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada. [2] Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Babaeijandaghi F; 1] Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada. [2] Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Low M; 1] Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada. [2] Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Chang CK; 1] Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada. [2] Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Lee ST; Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada.
  • Fiore D; Department of Experimental Medicine, Section of Medical Pathophysiology Food Science and Endocrinology, Sapienza University of Rome, Rome, Italy.
  • Zhang RH; 1] Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada. [2] Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Natarajan A; 1] Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada. [2] Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
  • Nedospasov SA; 1] Engelhardt Institute of Molecular Biology, Moscow, Russia. [2] Lomonosov Moscow State University, Moscow, Russia. [3] German Rheumatism Research Center, Berlin, Germany.
  • Rossi FM; 1] Biomedical Research Centre, University of British Columbia, Vancouver, British Columbia, Canada. [2] Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Nat Med ; 21(7): 786-94, 2015 Jul.
Article em En | MEDLINE | ID: mdl-26053624
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Células-Tronco / Fator de Necrose Tumoral alfa / Apoptose / Músculo Esquelético / Adipogenia / Doenças Musculares Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Células-Tronco / Fator de Necrose Tumoral alfa / Apoptose / Músculo Esquelético / Adipogenia / Doenças Musculares Limite: Animals Idioma: En Ano de publicação: 2015 Tipo de documento: Article