Recent advances in functional assays of transcriptional enhancers.
Genomics
; 106(3): 137-139, 2015 Sep.
Article
em En
| MEDLINE
| ID: mdl-26100358
ABSTRACT
In this special edition of Genomics, we present reviews of the current state of the field in identifying and functionally understanding transcriptional enhancers in cells and developing tissues. Typically several enhancers coordinate the expression of an individual target gene, each controlling that gene's expression in specific cell types at specific times. Until recently, identifying each gene's enhancers had been challenging because enhancers do not occupy prescribed locations relative to their target genes. Recently there have been powerful advances in DNA sequencing and other technologies that make it possible to identify the majority of enhancers in virtually any cell type of interest. The reviews in this edition of Genomics highlight some of these new and powerful approaches.
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MEDLINE
Assunto principal:
Transcrição Gênica
/
Elementos Facilitadores Genéticos
/
Genômica
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article