Autophagy mechanisms in sputum and peripheral blood cells of patients with severe asthma: a new therapeutic target.

Ban, G-Y; Pham, D L; Trinh, T H K; Lee, S-I; Suh, D-H; Yang, E-M; Ye, Y-M; Shin, Y S; Chwae, Y-J; Park, H-S

Ban, G-Y; Pham, D L; Trinh, T H K; Lee, S-I; Suh, D-H; Yang, E-M; Ye, Y-M; Shin, Y S; Chwae, Y-J; Park, H-S.

Afiliação

Ban GY; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea.
Pham DL; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea.
Trinh TH; Department of Biomedical Sciences, The Graduate School, Ajou University, Suwon, South Korea.
Lee SI; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea.
Suh DH; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea.
Yang EM; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea.
Ye YM; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea.
Shin YS; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea.
Chwae YJ; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea.
Park HS; Department of Biomedical Sciences, The Graduate School, Ajou University, Suwon, South Korea.

Clin Exp Allergy ; 46(1): 48-59, 2016 Jan.

Article em En | MEDLINE | ID: mdl-26112695

Assuntos

Asma/etiologia; Asma/metabolismo; Autofagia; Leucócitos/imunologia; Leucócitos/metabolismo; Escarro/citologia; Escarro/imunologia; Adulto; Proteínas Reguladoras de Apoptose/genética; Asma/diagnóstico; Asma/terapia; Proteína 5 Relacionada à Autofagia; Proteína Beclina-1; Estudos de Casos e Controles; Linhagem Celular; Citocinas; Feminino; Volume Expiratório Forçado; Técnicas de Silenciamento de Genes; Granulócitos/imunologia; Granulócitos/metabolismo; Humanos; Imunoglobulina E/imunologia; Contagem de Leucócitos; Masculino; Proteínas de Membrana/genética; Proteínas Associadas aos Microtúbulos/genética; Pessoa de Meia-Idade; Fagossomos/metabolismo; Índice de Gravidade de Doença; Adulto Jovem

Palavras-chave

autophagy; eosinophils; epithelial cells; severe asthma; treatment

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Autofagia / Escarro / Leucócitos Tipo de estudo: Diagnostic_studies / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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