Weight change after 20 years of age and the incidence of dyslipidemia: a cohort study of Japanese male workers.
J Public Health (Oxf)
; 38(2): e77-83, 2016 06.
Article
em En
| MEDLINE
| ID: mdl-26199305
ABSTRACT
BACKGROUND:
While heavier weight is known to increase the incidence of dyslipidemia, limited data are available on the relationship between weight gain and its development.METHODS:
A total of 2647 males were categorized into the following four groups according to the difference between their self-reported weight at 20 years of age and their measured weight in 1994-95 a loss of ≥5% (decrease), loss of <5% or gain of <5% (no change), gain of ≥5 to <15% (increase) and gain of ≥15% (sizable increase). They were followed up until their 2002-03 health examination. Using the 'no change' group as reference, the multivariable-adjusted odds ratio (adjusted for age, body mass index at 20 years of age, physical activity, smoking and alcohol intake) and 95% confidence interval (95% CI) for the incidence of dyslipidemia were determined using logistic regression models.RESULTS:
A total of 1342 participants developed dyslipidemia during the follow-up period. The 'increase' and 'sizable increase' groups had odds ratios for the incidence of dyslipidemia of 1.97 (95% CI, 1.59-2.45) and 2.68 (2.15-3.34), respectively, demonstrating that there was a significant dose-response association between weight gain since 20 years of age and the incidence of dyslipidemia (P < 0.001 for trend).CONCLUSION:
These results suggest that dyslipidemia could be prevented by avoiding weight gain in adulthood.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Aumento de Peso
/
Redução de Peso
/
Dislipidemias
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
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Humans
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Male
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Middle aged
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article