A multicenter photoprovocation study to identify potential biomarkers by global peptide profiling in cutaneous lupus erythematosus.

Calderon, C; Zucht, H D; Kuhn, A; Wozniacka, A; Szepietowski, J C; Nyberg, F; Weichenthal, M; Piantone, A; Budde, P

Calderon, C; Zucht, H D; Kuhn, A; Wozniacka, A; Szepietowski, J C; Nyberg, F; Weichenthal, M; Piantone, A; Budde, P.

Afiliação

Calderon C; Compound Development, Janssen Research & Development, LLC, USA CCalder2@its.jnj.com.
Zucht HD; Formerly of Digilab BioVisioN GmbH, Germany; currently of Protagen AG, Dortmund, Germany.
Kuhn A; Interdisciplinary Center for Clinical Trials (IZKS), University Medical Center Mainz, Germany (research conducted at Department of Dermatology, University of Duesseldorf, Germany).
Wozniacka A; Department of Dermatology and Venereology, Medical University of Lodz, Poland.
Szepietowski JC; Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Poland.
Nyberg F; Institution for Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Sweden; research conducted at Department of Dermatology, Danderyd Hospital, Stockholm, Sweden.
Weichenthal M; Department of Dermatology, Venerology and Allergology, University Hospital of Schleswig-Holstein, Germany.
Piantone A; Compound Development, Janssen Research & Development, LLC, USA.
Budde P; Formerly of Digilab BioVisioN GmbH, Germany; currently of Protagen AG, Dortmund, Germany.

Lupus ; 24(13): 1406-20, 2015 Nov.

Article em En | MEDLINE | ID: mdl-26206719

Assuntos

Lúpus Eritematoso Cutâneo/metabolismo; Peptídeos/sangue; Transtornos de Fotossensibilidade/metabolismo; Pele/metabolismo; Biomarcadores/metabolismo; Biópsia; Relação Dose-Resposta à Radiação; Humanos; Lúpus Eritematoso Cutâneo/sangue; Lúpus Eritematoso Cutâneo/patologia; Transtornos de Fotossensibilidade/sangue; Transtornos de Fotossensibilidade/diagnóstico; Pele/patologia; Pele/efeitos da radiação; Raios Ultravioleta; Microglobulina beta-2/metabolismo; beta-Defensinas/metabolismo

Palavras-chave

Cutaneous lupus erythematosus; lupus erythematosus; peptides; peptidomics; photoprovocation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Transtornos de Fotossensibilidade / Pele / Lúpus Eritematoso Cutâneo Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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