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Proteolytic Cleavage of AMPKα and Intracellular MMP9 Expression Are Both Required for TLR4-Mediated mTORC1 Activation and HIF-1α Expression in Leukocytes.
Zhang, Zhiyong; Amorosa, Louis F; Coyle, Susette M; Macor, Marie A; Lubitz, Sara E; Carson, Jeffrey L; Birnbaum, Morris J; Lee, Leonard Y; Haimovich, Beatrice.
Afiliação
  • Zhang Z; Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903;
  • Amorosa LF; Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903; and.
  • Coyle SM; Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903;
  • Macor MA; Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903;
  • Lubitz SE; Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903; and.
  • Carson JL; Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903; and.
  • Birnbaum MJ; Institute of Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Lee LY; Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903;
  • Haimovich B; Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08903; haimovic@rwjms.rutgers.edu.
J Immunol ; 195(5): 2452-60, 2015 Sep 01.
Article em En | MEDLINE | ID: mdl-26232429
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Metaloproteinase 9 da Matriz / Complexos Multiproteicos / Subunidade alfa do Fator 1 Induzível por Hipóxia / Receptor 4 Toll-Like / Proteínas Quinases Ativadas por AMP / Serina-Treonina Quinases TOR / Leucócitos Tipo de estudo: Prognostic_studies Limite: Aged / Animals / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Metaloproteinase 9 da Matriz / Complexos Multiproteicos / Subunidade alfa do Fator 1 Induzível por Hipóxia / Receptor 4 Toll-Like / Proteínas Quinases Ativadas por AMP / Serina-Treonina Quinases TOR / Leucócitos Tipo de estudo: Prognostic_studies Limite: Aged / Animals / Female / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article