Biopolymer-Based Delivery Systems: Challenges and Opportunities.
Curr Top Med Chem
; 16(9): 1026-39, 2016.
Article
em En
| MEDLINE
| ID: mdl-26303423
ABSTRACT
Biopolymer-based nanostructures or microstructures can be fabricated with different compositions, structures, and properties so that colloidal delivery systems can be tailored for specific applications. These structures can be assembled using various approaches, including electrospinning, coacervation, nanoprecipitation, injection, layer-by-layer deposition, and/or gelation. A major application of biopolymer-based particles is to encapsulate, protect, and release active molecules in the agricultural, food, supplements, personal care, and pharmaceutical sectors. The inherent variability and complexity of biopolymers (proteins and polysaccharides) often makes it challenging to produce particles with well-defined physicochemical and functional attributes. In this review, we discuss the properties of biopolymers, common particle fabrication methods, and some of the major challenges and opportunities associated with developing biopolymer-based particles for application as food-grade delivery systems.
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Base de dados:
MEDLINE
Assunto principal:
Biopolímeros
/
Sistemas de Liberação de Medicamentos
Limite:
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article