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A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants.
Khan, David D; Lagerbäck, Pernilla; Cao, Sha; Lustig, Ulrika; Nielsen, Elisabet I; Cars, Otto; Hughes, Diarmaid; Andersson, Dan I; Friberg, Lena E.
Afiliação
  • Khan DD; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden david.khan@farmbio.uu.se.
  • Lagerbäck P; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
  • Cao S; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
  • Lustig U; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
  • Nielsen EI; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.
  • Cars O; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
  • Hughes D; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
  • Andersson DI; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
  • Friberg LE; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.
J Antimicrob Chemother ; 70(11): 3051-60, 2015 Nov.
Article em En | MEDLINE | ID: mdl-26349518
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ciprofloxacina / Farmacorresistência Bacteriana / Escherichia coli / Viabilidade Microbiana / Antibacterianos Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ciprofloxacina / Farmacorresistência Bacteriana / Escherichia coli / Viabilidade Microbiana / Antibacterianos Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2015 Tipo de documento: Article