Tetracycline antibiotics impair mitochondrial function and its experimental use confounds research.

Chatzispyrou, Iliana A; Held, Ntsiki M; Mouchiroud, Laurent; Auwerx, Johan; Houtkooper, Riekelt H

Chatzispyrou, Iliana A; Held, Ntsiki M; Mouchiroud, Laurent; Auwerx, Johan; Houtkooper, Riekelt H.

Afiliação

Chatzispyrou IA; Laboratory Genetic Metabolic Diseases, Academic Medical Center, Amsterdam, the Netherlands.
Held NM; Laboratory Genetic Metabolic Diseases, Academic Medical Center, Amsterdam, the Netherlands.
Mouchiroud L; Laboratory for Integrative and Systems Physiology, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Auwerx J; Laboratory for Integrative and Systems Physiology, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland. r.h.houtkooper@amc.nl admin.auwerx@epfl.ch.
Houtkooper RH; Laboratory Genetic Metabolic Diseases, Academic Medical Center, Amsterdam, the Netherlands. r.h.houtkooper@amc.nl admin.auwerx@epfl.ch.

Cancer Res ; 75(21): 4446-9, 2015 Nov 01.

Article em En | MEDLINE | ID: mdl-26475870

Assuntos

Antibacterianos/farmacologia; Doxiciclina/farmacologia; Mitocôndrias/efeitos dos fármacos; Biossíntese de Proteínas/efeitos dos fármacos; Inibidores da Síntese de Proteínas/farmacologia; Animais; Humanos; Camundongos; Mitocôndrias/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biossíntese de Proteínas / Inibidores da Síntese de Proteínas / Doxiciclina / Antibacterianos / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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