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Pancreatic ß cell enhancers regulate rhythmic transcription of genes controlling insulin secretion.
Perelis, Mark; Marcheva, Biliana; Ramsey, Kathryn Moynihan; Schipma, Matthew J; Hutchison, Alan L; Taguchi, Akihiko; Peek, Clara Bien; Hong, Heekyung; Huang, Wenyu; Omura, Chiaki; Allred, Amanda L; Bradfield, Christopher A; Dinner, Aaron R; Barish, Grant D; Bass, Joseph.
Afiliação
  • Perelis M; Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Marcheva B; Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Ramsey KM; Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Schipma MJ; Center for Genetic Medicine, Northwestern University, Chicago, IL 60611, USA.
  • Hutchison AL; Medical Scientist Training Program, University of Chicago, Chicago, IL 60637, USA. Graduate Program in the Biophysical Sciences, University of Chicago, Chicago, IL 60637, USA. James Franck Institute, University of Chicago, Chicago, IL 60637, USA.
  • Taguchi A; Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Peek CB; Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Hong H; Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Huang W; Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Omura C; Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Allred AL; Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Bradfield CA; McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, WI 52705, USA.
  • Dinner AR; Graduate Program in the Biophysical Sciences, University of Chicago, Chicago, IL 60637, USA. James Franck Institute, University of Chicago, Chicago, IL 60637, USA. Department of Chemistry, University of Chicago, Chicago, IL 60637, USA.
  • Barish GD; Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
  • Bass J; Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. j-bass@northwestern.edu.
Science ; 350(6261): aac4250, 2015 Nov 06.
Article em En | MEDLINE | ID: mdl-26542580
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação da Expressão Gênica / Elementos Facilitadores Genéticos / Ritmo Circadiano / Células Secretoras de Insulina / Insulina Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação da Expressão Gênica / Elementos Facilitadores Genéticos / Ritmo Circadiano / Células Secretoras de Insulina / Insulina Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2015 Tipo de documento: Article