Key role of pancreatic stellate cells in pancreatic cancer.

Pothula, Srinivasa P; Xu, Zhihong; Goldstein, David; Pirola, Romano C; Wilson, Jeremy S; Apte, Minoti V

Pothula, Srinivasa P; Xu, Zhihong; Goldstein, David; Pirola, Romano C; Wilson, Jeremy S; Apte, Minoti V.

Afiliação

Pothula SP; Pancreatic Research Group, South Western Sydney Clinical School, Faculty of Medicine, The University of New South Wales, Sydney, Australia; Ingham Institute for Applied Medical Research, Liverpool, NSW, Australia.
Xu Z; Pancreatic Research Group, South Western Sydney Clinical School, Faculty of Medicine, The University of New South Wales, Sydney, Australia; Ingham Institute for Applied Medical Research, Liverpool, NSW, Australia.
Goldstein D; Pancreatic Research Group, South Western Sydney Clinical School, Faculty of Medicine, The University of New South Wales, Sydney, Australia.
Pirola RC; Pancreatic Research Group, South Western Sydney Clinical School, Faculty of Medicine, The University of New South Wales, Sydney, Australia; Ingham Institute for Applied Medical Research, Liverpool, NSW, Australia.
Wilson JS; Pancreatic Research Group, South Western Sydney Clinical School, Faculty of Medicine, The University of New South Wales, Sydney, Australia; Ingham Institute for Applied Medical Research, Liverpool, NSW, Australia.
Apte MV; Pancreatic Research Group, South Western Sydney Clinical School, Faculty of Medicine, The University of New South Wales, Sydney, Australia; Ingham Institute for Applied Medical Research, Liverpool, NSW, Australia. Electronic address: m.apte@unsw.edu.au.

Cancer Lett ; 381(1): 194-200, 2016 10 10.

Article em En | MEDLINE | ID: mdl-26571462

Assuntos

Neoplasias Pancreáticas/patologia; Células Estreladas do Pâncreas/patologia; Células Estromais/patologia; Microambiente Tumoral; Animais; Antineoplásicos/uso terapêutico; Comunicação Celular; Humanos; Terapia de Alvo Molecular; Neoplasias Pancreáticas/tratamento farmacológico; Neoplasias Pancreáticas/metabolismo; Células Estreladas do Pâncreas/efeitos dos fármacos; Células Estreladas do Pâncreas/metabolismo; Transdução de Sinais; Células Estromais/efeitos dos fármacos; Células Estromais/metabolismo

Palavras-chave

Desmoplastic reaction; Pancreatic cancer; Pancreatic stellate cells; Stromaltumour interactions; Tumour microenvironment

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Células Estromais / Células Estreladas do Pâncreas / Microambiente Tumoral Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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