[Para-Aortic Lymphadenectomy and Subsequent Chemotherapy after Resection of the Primary Lesion for Poorly Differentiated Adenocarcinoma of the Sigmoid Colon - A Case Report].
Gan To Kagaku Ryoho
; 42(11): 1435-7, 2015 Nov.
Article
em Ja
| MEDLINE
| ID: mdl-26602407
The patient was a 68-year-old male who had bloody stools. A colonoscopy revealed a sigmoid colon stricture, and a histological examination confirmed the presence of a poorly differentiated adenocarcinoma.Computed tomography revealed the involvement of a para-aortic lymph nodes, without other metastatic lesions. The patient underwent a sigmoidectomy (with regional lymph node dissection) and a para-aortic lymph node biopsy to prove the histological conformation. Subsequently, he was provided with 6 courses of modified FOLFOX6(mFOLFOX6) chemotherapy, resulting in a marked decrease in para-aortic lymph node involvement. He subsequently underwent a para-aortic lymphadenectomy. The resected specimen was mostly composed of fibrous degenerative tissue; viable cancer cells were observed only in a 2-mm² area. The patient was provided with 6 more courses of mFOLFOX6 chemotherapy, and has since been free of recurrence (for 6 years and 1 month after the second surgery).
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias do Colo Sigmoide
/
Adenocarcinoma
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Protocolos de Quimioterapia Combinada Antineoplásica
/
Excisão de Linfonodo
Limite:
Aged
/
Humans
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Male
Idioma:
Ja
Ano de publicação:
2015
Tipo de documento:
Article